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imitrex rebound headaches


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Maximum osmotic gradient, and thus have the effect of dehydration mannitol and urea, which should be applied to a sharp rise in intracranial pressure and cerebral edema, mannitol reduces intracranial pressure by 50-90%, effective for 4-7 hours. His single dose equal to 0,5-1,0 g of dry matter by a 1 kg (daily dose - 1.5 g / kg) administered intravenously in a 10-20% solution. Introduction of mannitol is better to start slow bolus or infusion rapidly (100 drops in 1 min.) With a gradual slowing down to 30-40 drops in 1 min. In the application of mannitol to monitor urine output, as in violation of renal filtration effect of its introduction may be missing.
imitrex rebound headaches